Medical Informatics
Viral infections are a major public health problem. Understanding their biology, mechanisms of pathogenesis, epidemiology, and interactions with the immune system are critical to the development of vaccines and antivirals. Widely distributed geographically dengue virus (DENV) causes the most prevalent human mosquito-borne viral disease worldwide. DENV may cause a spectrum of disease manifestations, ranging from classical dengue fever (DF) to more severe dengue hemorrhagic fever (DHF) and dengue